Microneedling Safety Tips & Best Practices
Special Area Depth Recommendations
Some areas of the face are more sensitive or closer to bone, so it's important to use lower needle depths for safety and comfort. Here's a quick guide:
- Forehead: 0.25–0.5 mm
- Nose: 0.25 mm
- Chin & Cheekbones: 0.25–0.5 mm
Always use extra care around these areas to avoid irritation or over-penetration.
Infusion Safety: Not All Serums Are Equal
Not all serums are safe for infusion or immediate use after microneedling, especially those containing active ingredients like Vitamin C, Salicylic Acid, or Retinoids. Only use them if the formula is specifically made for post-treatment or infusion.
Any serum to pair with microneedling, make sure it is:
- Fragrance-free
- Alcohol-free
- Clearly labeled as safe for microneedling or infusion use
When to Apply Certain Active Ingredients
Vitamin C & Salicylic Acid: Can be irritating right after treatment. Unless the product is designed for microneedling, it’s best to wait 24–48 hours and only apply if your skin isn’t sensitive.
Retinoids: Should be used only after the skin has healed, typically 3–5 days after treatment, especially when using deeper needle depths (1.0 mm or more).
Home Use Guidelines
If you're doing microneedling at home, it's safest to use needle depths under 1.0 mm.
Anything deeper should be left to professionals to avoid potential skin damage or infection.
Recommended Serums for Microneedling
Explore our curated serum collections designed to pair perfectly with microneedling:
Selenderm Peptain P5 Ampoules – Infusion-safe ampoules targeting specific skin concerns:
Brightening: Fades dark spots and evens skin tone
Moisture: Boosts hydration and reinforces the skin barrier
AC FLU: Calms sensitive, acne-prone, or inflamed skin
Repair (Firming): Improves elasticity and reduces fine lines
HISTOLAB Functional Serums – Daily-use (or nanoneedling) clinical formulas trusted by skincare professionals:
Hyaluron 62: Hydrating support before and after treatment
EGF 63: Firming and wrinkle care with peptide-rich EGF
Vita C 47: Brightens and evens skin tone
Azulene 72: Soothes redness and supports oily, sensitive skin