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Bio Pen Q2 Microneedling Device with Bonus Cartridges – 2×9 Pin, 2×14 Pin, 1×Nano
FREE SHIPPING FROM THE USA
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50ml Serum
Shipping: Free standard shipping (3-8 business days) for all U.S. orders. Express and international shipping options available at checkout.
Returns: 30-day return policy for unused and sealed items. For more details, please visit our full Shipping & Return Policy.
Formulated for targeted results and daily care, each HISTOLAB ampoule serum addresses a specific skin concern with clinical-grade ingredients trusted by 10,000+ dermatology clinics.
Hyaluron Complex Ampoule 83 – 83% Hyaluronic Acid Complex (was 62%)
Delivers intense, long-lasting hydration to plump and nourish dry or dehydrated skin. Also great for pre- and post-microneedling care.
EGF Complex Ampoule 63 – 63% EGF Peptide Complex
Visibly smooths fine lines and improves elasticity with EGF peptides and adenosine to support firmer, more youthful-looking skin.
Vita C Complex Ampoule 47 – 47% Vitamin C Complex
Brightens dull skin, fades dark spots, and evens skin tone with a powerful blend of stabilized vitamin C and arbutin.
Azulene Complex Ampoule 72 – 72% Azulene Complex
Calms redness, controls oil, and soothes irritated or acne-prone skin with azulene, tea tree oil, and BHA.
HISTOLAB products are made in South Korea and are trusted by nearly 10,000 dermatological and aesthetic clinics worldwide. Developed with dermatologists and powered by Plant Stem Cell (Callus) technology, HISTOLAB offers professional-grade skincare backed by clinical research and KFDA approval.
50 ml
Our clinic-grade ampoules are designed to support your skin’s specific needs with flexible use in your routine:
Microneedling
Hyaluron Complex Ampoule 83 is ideal for use before and after microneedling treatments. It delivers deep hydration, soothes the skin, and supports recovery for optimal post-care results.
Nano-Needling & Daily Skincare
All four ampoules can be safely used for nano-needling or as part of your daily skincare routine to boost results and deliver functional benefits:
EGF Complex Ampoule 63 – Smooths fine lines and improves skin elasticity.
Hyaluron Complex Ampoule 83 – Deeply hydrates and plumps dry, tired skin.
Vita C Complex Ampoule 47 – Brightens the complexion and fades dark spots.
Azulene Complex Ampoule 72 – Calms redness, reduces oil, and soothes sensitive, acne-prone skin.
Use these serums after cleansing and toning, either alone or with nano-needling, for maximum results.
Note: The ampoules should not be used for infusion, as they are not formulated for deep skin penetration.

Overall rating: 4.8 / 5 from 113 reviews.
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Davidxia V. 5/5 Verified
Bio Pen Q2 Microneedling Device with Bonus Cartridges – 2×9 Pin, 2×14 Pin, 1×Nano
Excellent
Davidxia V. 5/5 Verified
I am so happy I found Derma Queen! I get all my serums, and cartridges from them! High quality, decent prices, and good customer service!
Chloe A. 5/5 Verified
Derma Queen, is a fantastic company! High quality devices,serums, and cartridges, for decent prices! Great customer service too,😊.
Chloe A. 5/5 Verified
very well package, and sealed.
Milagros D. 5/5 Verified
Love it!!!!
Ma Kristina A. 5/5 Verified
Love doing this everymonth
Ma Kristina A. 5/5 Verified
Nice job
Geovani R. 5/5 Verified
Loving it
Michelle L. 4/5 Verified
I love the hydrapen for microneedling! It gives all the hydration that you would want while microneedling!
Dorene G. 5/5 Verified
Hydra Pen H6 Advanced Serum Infusion Microneedling Pen with Light Therapy
Just what I needed! They add such luxury to the hydra pen!
Dorene G. 5/5 Verified
It was exactly what I had been missing! Light and rich all rolled into one! Luxury at it's finest!
Dorene G. 5/5 Verified
ASCE Plus SRLV Exosome Advanced Skin Booster with ExoSCRT™ Technology
I love it está más que genial podría pasar todo el tiempo usándola
Esmeralda R. 5/5 Verified
Bio Pen Q2 3-in-1 Microneedling Device with EMS Microcurrent & LED Light Therapy
Great device, easy to use, fast shipping. Loving it !!
Maria M. 5/5
Dr. Pen M8S Microneedling Pen – Advanced Skin Care Tool for Professional and Home Use
Very nice tool! I loved 🌷
Beatriz U. 4/5 Verified
These needles are thin, flexible, and comfortable for the face. They are the real deal, I will for sure be buying the A11 needles from Derma Queen again. Thanks so much!
Angie B. 5/5 Verified
Amazing new tool, amazing results and I do highly recommend it for everyone that is looking for a new glow and healthy skin!!!
Cynthia L. 5/5 Verified
Very satisfied with all my purchases from Derma Queen! Fast delivery, professional service! Thank you
Oxana G. 5/5 Verified
Chose #3 setting on cartridge and #5 setting on hydrapen. Worked great, skin feels moist and plump.
Czarina D. 5/5 Verified
Dr.Youheal PDRN Plus Ampoule - Advanced Anti-Aging Wrinkle Care & Moisturizing
Difficult to use, I had to change the cartridge/needle 3x due to serum not coming out. I followed all the instructions with the serum flow and speed but still had trouble. However, the ASCE+ exosome worked great after only 1 session.
Czarina D. 3/5 Verified
Effective in improving skin texture and tone after one session.
Czarina D. 5/5 Verified
ASCE Plus SRLV Exosome Advanced Skin Booster with ExoSCRT™ Technology
Excelente
Julieth M. 5/5 Verified
I love it and so far my client loved her results as well
Elisa M. 5/5 Verified
Absolutely love my Biopen!
Shannon J. 5/5 Verified
Bio Pen Q2 Microneedling Device with Bonus Cartridges – 2×9 Pin, 2×14 Pin, 1×Nano
Can’t wait to use my pen! Will post an update review soon!
Linh D. 5/5 Verified
Sealed, sterile and ready for use!
Linh D. 5/5 Verified
Perfect and good quality and I love the color
Krisztina K. 5/5 Verified
Dr. Pen A6S Smart Microneedling Derma Pen Professional Wireless Skincare Kit
Quality and easy to use
Krisztina K. 5/5 Verified
Great product easy to use
Krisztina K. 5/5 Verified
Dr. Pen Hydra H3 Pen All In One Microneedling Device for Skin Care at Home
Excellent equipment
Gabriela V. 5/5 Verified
Love love love this device!!!! Who doesn't want a little more tightening??? Can't wait to use this on my clients!!!
Kristy F. 4/5 Verified
This is a great pen! I love the extra batteries!
Renae B. 5/5 Verified
Dr. Pen A6S Smart Microneedling Derma Pen Professional Wireless Skincare Kit
These are both great! Thank you!!
Renae B. 5/5 Verified
I’ve been looking for a reliable place to buy cartridges and tried a few different platforms. This one looks legit!
Anonymous 5/5 Verified
Got the Dr. Pen and cartridges quickly and as described. Everything’s been working great so far. Shipping from the USA was a plus! I’ll definitely be ordering again. Thanks!
Anonymous 5/5 Verified
Dr. Pen M8S Microneedling Pen – Advanced Skin Care Tool for Professional and Home Use
I love my biopen, I had to purchase the 14 pin cartridges. And of course, I want to try the infusion serums. Derma queen is amazing!! 😍❤️
Davidxia V. 5/5 Verified
Loved what it did to my skin it looks smooth and hydrated.
David G. 5/5 Verified
I just recived my order. It was completely warm. I opened the package and noted those small icepacks were very warm. I am not sure if the content in the vial will be effective since it was warmer than room temperature when I received it.
Zahra M. 1/5 Verified
Fast delivery-Thank you!
Lynda J. 5/5 Verified
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Jolanta T. 5/5 Verified